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First 21® Nutritional Supplement for Milk and Milk Replacer

SKU: A0083 Categories: , ,
First 21 Bucket

$230.00

First 21 is designed specifically to support calves during the critical period between initial colostrum feeding and the development of the calf’s own immune system, which typically occurs between one and two months of age.

A nutritional supplement, First 21 helps promote immune function, gut health, and calf growth during the first three weeks of life using a unique blend of colostrum, plasma proteins, egg-yolk antibodies, and direct-fed microbials.

  • Helps bridge the critical immunity gap during the first 21 days of life
  • Supports calf immune function after maternal colostrum or colostrum replacer feeding
  • Promotes digestive health and gut integrity
  • Helps reduce scours and digestive challenges
  • Encourages improved starter intake and feed utilization
  • Supports calf growth and early-life development
  • Contains direct-fed microbials to support beneficial gut bacteria

Product Details

Description

The first few weeks of a calf’s life are critical for long-term health and performance. After calves receive antibodies from maternal colostrum or colostrum replacer, they enter a vulnerable transition period before their own immune systems are fully developed.

This stage, often called the “immunity gap,” can increase the risk of digestive challenges, scours, reduced feed intake, and slower growth.

First 21 is specifically designed to help bridge this critical immunity gap during the first three weeks of life. As a nutritional supplement, First 21 provides research-supported ingredients that help support calf immunity, digestive health, and growth performance during this important stage of development.

First 21 Supplement can be added to pasteurized whole milk or calf milk replacer. Ideal for producers who:

  • Feed pasteurized whole milk
  • Use an existing milk replacer program
  • Want additional immune and digestive support during the first weeks of life

 

Directions for Use

  • Add 1.2 oz. (35 grams) of First 21 Supplement to pasteurized whole milk or calf milk replacer.
  • Feed 1.2 oz. per calf per feeding.
  • Feed twice daily for two to three weeks for best results.

Mixing Recommendations

  • Use the enclosed scoop for approximate measuring.
  • Weigh powder for accurate mixing and consistency.

Storage

  • Store in cool, dry place.
  • Keep container tightly closed when not in use.

Ingredients

First 21 combines functional proteins and bioactive ingredients from three natural antibody sources:

  • Dried Bovine Colostrum provides immunoglobulins (IgG) and functional proteins that help support calf immunity and digestive health.
  • Spray-Dried Plasma supplies highly functional proteins that support gut integrity, feed intake, and calf performance.
  • Egg-Yolk Antibodies (IgY) help support a healthy intestinal environment and digestive function during early calf development.
  • Tri-Mic WD Direct-Fed Microbial contains a source of live, naturally occurring microorganisms to support beneficial gut microflora and digestive health. Research-supported benefits include:
      • Competitive exclusion of pathogens
      • Reduced scours
      • Improved feed intake and utilization
      • Enhanced calf growth and development

Available size

First 21 Supplement – 20lb. pail

  • Approximately 259 feedings per pail
  • Includes enclosed scoop holding approximately 1.2 oz. (35 grams)

 

Frequently Asked Questions 

Is First 21 a colostrum replacer?
No. First 21 is not a colostrum replacer. It is designed to be fed after maternal colostrum or colostrum replacer to help support calves during the critical immunity gap before their own immune systems are fully developed.

What is the immunity gap in calves?
The immunity gap is the period after calves receive antibodies from colostrum but before their own immune systems are fully functioning. This stage can increase the risk of digestive challenges and reduced calf performance.

Can First 21 be added to whole milk?
Yes. First 21 Supplement is specifically designed to be mixed into pasteurized whole milk or calf milk replacer.

How long should calves receive First 21?
For best results, feed First 21 twice daily for two to three weeks during the critical early-life period.

What makes First 21 different from other calf supplements?
First 21 combines three natural antibody sources: bovine colostrum, plasma proteins, and egg-yolk antibodies, along with direct-fed microbials to help support calf immunity, gut health, and growth.

Does First 21 contain probiotics?
Yes. First 21 contains Tri-Mic WD direct-fed microbials, a source of live, naturally occurring microorganisms that support beneficial gut bacteria and digestive health.

Should I choose the supplement or complete milk replacer?
The supplement is ideal for producers feeding pasteurized whole milk or an existing milk replacer program. The complete milk replacer provides the same support benefits in a complete feeding solution.

Additional information

Weight 22 lbs
Dimensions 16 × 12 × 12 in
Options

First 21 Supplement

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